Psilocybin Science and Research

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Cardiovascular Safety of Psychedelics: What do we really know?
This review examines the cardiovascular effects of psilocybin, LSD, and mescaline, highlighting safety in healthy users while outlining risks for at-risk populations.
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Postpartum Depression: A Role for Psychedelics?
This review of a recent publication in the Journal of Psychopharmacology explores whether psilocybin could help treat postpartum depression by improving mood and bonding, and examines early safety data for breastfeeding.
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Microdosing LSD for ADHD: Hype, hope, and the power of placebo: results from a randomised controlled trial
A first-of-its-kind clinical trial finds that low-dose LSD is safe for adults with ADHD but no more effective than placebo, underscoring the power of expectancy.
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Psilocybin and Neuroplasticity: Research & Benefits
We describe the most groundbreaking research in this area, including the most recent studies. This will enable you to get a better sense of not only how psilocybin can improve your mental health but also how to maximize these benefits.
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Does Antidepressant Discontinuation Affect Psilocybin's Benefits in Depression Treatment?
The study aimed to investigate the impact of discontinuing serotonergic antidepressants (SSRIs/SNRIs) prior to psilocybin therapy compared to continuing treatment with escitalopram for individuals with major depressive disorder (MDD).
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One vs. Two Psilocybin Doses: Unravelling the Evidence
This article delves into the current research, ongoing studies, and practical considerations surrounding this question, aiming to provide a comprehensive resource for mental health professionals and the general public interested in psychedelic treatments.
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Psilocybin Enhances Insightfulness in Meditation – A Neuroimaging Perspective
The study aimed to investigate how psilocybin affects brain activity during meditation and whether it enhances meditative states.
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Esketamine for Depression: What does the latest meta-analysis tell us?
This article reviews the latest meta-analysis on esketamine for depression, highlighting modest clinical effects, safety concerns, and its potential to reduce healthcare costs.
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Psilocybin and Sleep: Can better sleep enhance antidepressant effects?
This study reviews emerging evidence on the interplay between sleep and psilocybin therapy, highlighting how sleep quality may influence treatment outcomes for depression.
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Efficacy and Safety of Psilocybin in the Treatment of Major Depressive Disorder (MDD): A Meta-Analysis
This meta-analysis explores psilocybin's effectiveness and safety in treating major depressive disorder (MDD), with a particular focus on dose-response relationships and optimal timing of therapeutic effects.
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Psilocybin and Spiritual Practices as Catalysts for Enduring Psychological and Prosocial Change
This study explored how psilocybin combined with meditation and spiritual practices influences long-term psychological functioning and prosocial behaviors.
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How Odyssey is Science and Evidence-Based
The end-to-end Odyssey experience is modeled after best practices used in modern clinical trials and psychedelic research studies. This article describes the many ways in which our evidence-based approach is built on a foundation of science, from the ground up.
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Psilocybin Services: Taking Safety Seriously
Safety is our highest priority. Psilocybin experiences can be extremely powerful, and we believe they should be handled with intention, care, and respect. Accordingly, safety has been thoroughly considered through every step of the Odyssey process
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Challenging Psychedelic Experiences: Catalysts for Psychological Growth?
This article delves into how challenging psychedelic experiences, when properly supported, can serve as catalysts for profound personal transformation.
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Psilocybin and Personality Change: Can Psychedelic Therapy Reshape Traits Linked to Addiction?
This clinical trial explores how psilocybin therapy alters personality traits like neuroticism and impulsiveness, and how these changes may support addiction recovery.
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